General Odontology and Specialties

Unit Chief

PhD. Myriam Angélica de la Garza Ramos

Phone Number: +52(81) 1340 4370 ext 1816 or 1781

Unit Description

The General Odontology and Specialties has as main objective to develop treatments, models, and material to improve oral health. The Unit’s strategic plan continuously seeks the international presence through collaboration projects with international institutions, and with established research centers as well, not leaving behind academic collaboration with national institutions and research programs with local and national industries to improve potential antiseptic products.

Services

Molecular Detection in microorganisms via clinic real-time PCR and qPCR genic expression analysis of microorganisms.
Quorum Sensing and gene expression in natural germ habitat virulence.
Development and assistance to projects of microbial biochemistry, biotechnology, and microbial regulation processes in bioreactors areas.
Obtainment and identification of compounds of interest for the agri-food and health sectors.
Identification, extraction, and accumulation of bacteriocin produced in lactic acid bacteria metabolism (probiotics)
Relevant molecule identification stemming from natural extracts and/or use of organic residues of industrial processing.
Study of the antimicrobial, antifungal, bactericide and/or antibiotic effectivity and viability of relevant substances. Supported evidence by norms NMX-BB-040-SCFI-1999, CSL 27 No. 1, 2007 and Kirby Bauer methods 1966, Andrews JM 1991.
Natural product identification and its use in dental therapies.
Molecules derived from plant identification and its application on dental materials and its industrial use.
Epidemiologic studies of oral microbiomes.
Analgesic use of medicinal plants.
Epidemiologic studies of oral cancer.

Dra. Erandi Escamilla Garcia

Development and assistence in microbial biochemistry and biotechnology areas, as well as regulation of microbial processes in bioreactors.
Identification and recollection of pertinent compunds of the public health and agrofod sectors:

o Recollection, extraction, and identification of bacteriocins produced on probiotics metabolism.

o Natural extract molecule identification and/or the utilization of organic residues of industrial processes.

Programs

Academic Stay at the Universidad Javeriana, Bogota, Colombia.
Academic Stay at the Universidad de San Martín de Porres, Lima, Peru.
Academic Stay at the Louisville University, Kentucky.
Academic Stay at the Universidad Católica Los Ángeles Chimbote

Research:

Development of Nanomaterial for regenerative use of oral cavity tissue.
Development and usage of new alloys for dental prosthesis restauration.
Biomechanical models of robotic engineering, simulation of articulations, and dental prosthesis.

Facilities and Equipment

Anaerobiosis chamber
Autoclave
Incubator
Vortex-Genie
Class II Biosafety Bell*
Fume Extractor
Stereoscopic Microscope
Control Panel
Illumination Adaptor
Illumination Adaptor control
Control Unit
Lamp Module
Microscope
High-Resolution Microscopic Camera
White Light Source
Computer
Heating Plate

Publishing

Antimicrobial Effect of the Methanolic Extract Psacalium decompositum on Periodontopathogenic Bacteria P. García-Palencia, M.A. de la Garza-Ramos, S.A. Galindo-Rodríguez, A. Oranday-Cárdenas, C. Leos-Rivas, M.J. Verde-Star and C. Rivas-Morales ISSN 1811-7775

David Mizael Ortíz-Martinez, Catalina Rivas-Morales, Myriam Angelica de la Garza-Ramos, Maria Julia Verde-Star, Maria Adriana Nuñez-Gonzalez, and Catalina Leos-Rivas Antimicrobial effect of chalepensin against Miconia sp. Increases mRNA Levels of PPAR Gamma and Inhibits Alpha Amylase and Alpha Glucosidase Hindawi Publishing Corporation Evidence-Based Complementary and Alternative Medicine Volume 2016, Article ID 5123519, 6 pages http://dx.doi.org/10.1155/2016/5123519

Ricardo Gomez-Flores, Marcela Alejandra Gloria-Garza, Myriam Angélica de la Garza- Ramos, Ramiro Quintanilla-Licea and Patricia Tamez-Guerra Antibacterial effect of Chalepensin against Streptococcus mutans Vol. 10(36), pp. 631-634, 24 September, 2016 DOI: 10.5897/JMPR2016.6166 Article Number: EFB159B60764 ISSN 1996-0875 Copyright © 2016 Author(s) retain the copyright of this article http://www.academicjournals.org/JMP

Jorge A. Esquivel Valerio, Jacqueline Rodriguez Amado, Mario Alberto Garza Elizondo, Myriam Angelica De La Garza-Ramos DENTAL CONDITIONS IN RHEUMATIC DISEASES Revista Mexicana de estomatología Int Dent J. 2015 Oct;65(5):249-55. doi: 10.1111/idj.12177. Epub 2015 Sep 18.

Prevalence of caries and malocclusion in an indigenous population in Chiapas, Mexico. Aamodt K1, Reyna-Blanco O1, Sosa R2, Hsieh R1, De la Garza Ramos M3, Garcia Martinez M3, Orellana MF1.

DOI: 10.3923/ijp.2016.737.742 Int. J. Pharmacol. 1 2 (7): 737-742, 2016 International Journal of Pharmacology

Villarreal García LE., Sáenz Rangel S., Cruz Fierro N., López Villarreal SM. Rodríguez Luis OE, Alcázar

Pizaña AG., De la Garza Ramos MA., Escamilla García E. Evaluación de actividad antibacterial de Larrea

tidentata y Leucophyllum frutescens en bacterias de interés periodontal. Editor: Andrés Navarrete

Castro, Ph.D. ISSN: 0370-5943. Revista Latinoamericana de Química 43(133 Supl. Especial):

FAVP142.11° Reunión Internacional de Investigación en Productos Naturales

2015.

Escamilla García E., O’Riordan S., Gomes N., Aguedo M., Belo I., Teixeira J., Belin J-M., Waché Y. An air-lift biofilm reactor for the production of -decalactones by Yarrowia lipolytica. Process Biochemistry (Elsevier). 49(9):1377–1382.

L. Baca-Castañón, M. A. De la Garza-Ramos, A. G. Alcázar-Pizaña, A. Coronado-Mendoza, Y. Grondin, R. I. Sánchez-Najera, Carlos E. Medina De la Garzaand E. Escamilla-García*. Antimicrobial efect of Lactobacillus reuterion cariogenic Streptococcus gordonii, Streptococcus mutans, and periodontal disease Actinomyces naeslundii and Tannerella forsythensis bacteria. Probiotics and Antimicrobials Proteins (Springer). doi: 10.1007/s12602-014-9178-y. ISSN 1867-1306.

Effect of themoplastic Extrusion and Protease Suoolementation in red sorghum, Decoraticated sorghum and maize in the enzymatic hydrolysis efficiency as pretreatment for time process reduction.

Casiano Del Ángel-Mosqueda, Yolanda Gutiérrez-Puente, Ada P. López-Lozano, Ricardo E Romero-Zavaleta, Andrés Mendiola-Jiménez, Carlos E Medina-De la Garza, Marcela Márquez-M and Myriam A De La Garza-Ramos. (2015). Epidermal growth factor enhances osteogenic differentiation of dental pulp stem cells in vitro. Head & Face Medicine Editorial.

L. Baca-Castañón; M. A. De la Garza-Ramos; A. G. Alcázar-Pizaña; R. I. Sánchez-Najera; Carlos E. Medina De la Garza; E. Escamilla-García. Antimicrobial effect of lactobacillus reuteri on bacteria involved in periodontal disease and dental caries.90^th General Session & Exhibition of the IADR. Journal of Dental Research 90. Charlotte, NC (USA), Marzo 2014

Delgado-Arteaga, B.L. Mendoza-Mexicano, E. Mares-Favela, P. Torres, E. Escamilla-García, M.A. de la Garza-Ramos, A.G. Alcázar-Pizaña and R.V. Ruiz-Ramos. Antimicrobial activity of Clindamycin against Streptococcus mutans and Enterococcus faecalis. Journal of Dental Research. 93A(624). 90^th General Session & Exhibition of the IADR. Journal of Dental Research 90. Charlotte, NC (USA), Marzo2014

Erandi Escamilla-García; Andrea G. Alcázar-Pizaña; Myriam A. de la Garza-Ramos; Carlos E. Medina-De la Garza; Marcela Márquez; Anders R. Holmberg.Antimicrobial activity of CatDex against Porphyromonas gingivalis W83 and Streptococcus mutans UA130.91^th General Session & Exhibition of the IADR. Seattle, Washington (USA) 20-23. March 2013.

Incidence of Candida albicans in diabetic patients with a dental prosthesis in Northeast Mexico. African Journal of Microbiology Research. Vol 7(41): 4822-4847, 11 October, 2013. ISSN: 1996-0808. 2013

Elvia Denisse Mena-Mendivil; Jorge Jaime Flores-Treviño; Idalia Rodríguez-Delgado; Myriam A. de la Garza-Ramos; Hilda H. Torre-Martínez; Gustavo Israel Martínez- González. Antimicrobial effect of Microdacyn 60, OxOral, and sodium hypochlorite 5.25% in anaerobic bacteria. Journal of Pharmacognosy and Phytotherapy. Vol. 5(6), pp. 114-119, June, 2013

Garza-Garza Luis Carlos, Gallegos-Canales Anakaren, Elizondo-Garza Nemesio, Martínez- González Gustavo Israel and García-Palencia Patricia Titulo: Incidence of Candida albicans in diabetic patients with a dental prosthesis in Northeast Mexico. African Journal of Microbiology Research. 2013

Victor E. Aguirre-Arzola; Benito Pereyra-Alferez; Rosa Isela Sanchez-Najera; Luis J. Galan-Wong; Myriam A. De La Garza-Ramos; Andrea G. Alcazar Pizana. Evidence of cross gene regulation of some virulence factors of Porphyromonas gingivalis by Streptococcus intermedius. African Journal of Biotechnology. Vol. 12(28), pp. 4498-4502, 10 July, 2013

Evelyn Torres-Capetillo; Roberto Carrillo-Fuentevilla; Myriam A. De la Garza-Ramos; Roberto Mercado Hernández; Hilda H. H. Torre-Martínez; Juan Carlos Segoviano-Ramírez. Antimicrobial efficacy of neutral super-oxidized electrolyzed gel versus chlorhexidine digluconate 0.12% in biofilm formation on orthodontic mini-implants: An in vitro study. Journal of Pharmacognosy and Phytotherapy. Vol. 5(4): 64-71. 2013

Myriam A. De La Garza-Ramos; Jesús A. Valdez-Gonzalez, Rogelio A. Elizondo-Pereo, Benito Pereyra-Alférez; Raúl G. Caffesse; Francisco González-Salazar. Prevalence of Helicobacer pylori in saliva and dental plaque related to periodontal disease and gastritis. African Journal of Microbiology Research

Vol. 7(21): 2505-2509. 2013

R Hernandez-Delgadillo; D Velasco-Arias; D Diaz; K Arevalo-Niño; Garza-Enriquez Marianela; M.A. De la Garza-Ramos; C Cabral-Romero. Zerovalent bismuth nanoparticles inhibit streptococcus mutans growth and formation of biofilm. International Journal of Nanomedicine. Vol. 8(7): 520-524. ISSN: 1178-2013. 2012

Garzón-Cortés VDL, Guzman M.A; de la Garza-Ramos M.A; Martinez R. Reduction of inflammation of the surraunding tissue of a miniimplants in sus scrofa ussuricus using chlorexidine dicluconate gel. Journal of the American Association for Laboratory Animal Science. Vol. 51(5): 707-708. 2012

Miguel Angel Quiroga Garcia; Myriam Angelica De La Garza-Ramos; Jesus Amadeo Valdez Gonzalez. Consideraciones para el Manejo Odontológico del Paciente Diabético (Parte I). Avances Odontológicos. Vol. 6(7): 6-7. 2012. ISSN:01885812

Nalleli Rector Rubio; Fermin Guerra del Angel; Myriam Angelica De La Garza Ramos; Claudio Cabral Romero; Rogelio Oliva Perez; Hector Telles Limenez. Efectividad in vitro de la Clindamicina Gel sobre Bacterias Periodontopatogenas. Imbiomed. Vol. 42(42): 919-926. 2012. ISSN 1561-2880

Miguel Angel Quiroga Garcia; Myriam Angelica De La Garza Ramos; Jesus Amadeo Valdez Gonzalez. Cuidado del Paciente Diabético en el Consultorio Dental (Parte II). Avances Odontológicos. Vol. 2(2):1-3. 2012. ISSN 0188-5812

Baca Castañón M.L., Escamilla García E., De la Garza Ramos M.A., Rodríguez N. Efecto antimicrobiano de Lactobacillus reuteri en bacterias que intervienen en la enfermedad periodontal y la caries dental. Revista de Investigación en Odontología Clínica. Vol. 2: 48-49. 2012. ISSN: 2007-3291.

M.A de la Garza-Ramos; Maricela Janeth-Gamez Salas; Laura La-Rojo; María de Lourdes Verdugo-Barraza. Detection of microorganisms in patients with brackets MBT and Alexander. BioMicroWorl. Vol. 4(4): 966-967. 2011

Peralta-Contreras, S. Serna-Saldivar, E. Pérez-Carrillo, E. Escamilla-García, E. Aguilar-Zamarripa. Effect of thermoplastic extrusion of maize worts on the efficiency of bioethanol with Zymomonas mobilis. 11 AIChE Annual Meeting: Minneapolis, MN. American Institute of Chemical Engineers (AIChE) – Annual Conference Proceedings. 2011

Escamilla García; A. Alcázar Pizaña; M. A. de la Garza Ramos. Obtention of antimicrobial compounds by lactic acid bacteria: application in oral health.Proceding book. 89^th General Session & Exhibition of the IADR. Journal of Dental Research 90 (Special Issue A): 1394 (Microbiology/Immunology-Infection control). ISSN: 1072-3218. 2011

Alcázar Pizaña, E. Escamilla García, M. A. de la Garza Ramos and B. Pereyra Alférez (2011). Expression of genes from Porphyromonas gingivalis in mixed culture. Proceding book. 89^th General Session & Exhibition of the IADR. Journal of Dental Research 90(Special Issue A): 2757 (Microbiology/Immunology-Porphyromonas gingivalis). ISSN: 1072-3218. 2011

Gomez-Flores; R. González-Meléndez; A. Ceballos-Salobreña; P. Tamez-Guerra; R. Tamez-Guerra; C. Rodríguez-Padilla; E. Monreal-Cuevas; M. A. De La Garza-Ramos.Antimicrobial and antiinflammatory potential of the swedish herbs extract. European Journal of Medicinal Plants. Vol. 1(4):107-117. 2011

Geny Duran; Hilda H.H; Torre Martínez; Eduardo De La Rosa; M. De La Garza-Ramos; R. Mercado Hernández. Spap gene of streptococcus mutans in dental plaque and its relationship with early childhood caries. European Journal of Paediatric Dentistry. Vol. 4(18):220-240. 2011

Jose de Jesus Zermeño N; Clara Del Carmen Flores A; Donato Saldivar R; Juan Antonio Soria L; Miriam Garza R; Jose Luis Iglesias B. Enfermedad Periodontal como factor de riesgo para presentar resultados perinatales adversos. Revista Chilena de Obstetricia y Ginecología. Vol. 76(5): 338-343. 2011. ISSN: 0717-7526

M. Garza-Garza; J. C. Llodra-Calvo; A. Y. Arce-Mendoza; M.A.de la Garza-Ramos; M. Á. Quiroga-García. Detection of IGM and IGG antibodies against mycobacterium tuberculosis in students faculty of dentistry, University of Nuevo Leon, Mexico. BioMicroWorld. Vol. 4(4):324-325. 2011

De la Garza Ramos MA; Estrategia para el desarrollo de procesos biotecnológicos. La UANL, pionera en investigación y desarrollo en ciencias de la salud. En Ciencia Conocimiento Tecnología. 2011. Vol. 116: 48-49.

Alvarado Cárdenas G; Sosa Rivera A; Flores Treviño F; De la Garza-Ramos MA. Determinación de la Efectividad del Timsen, Hipoclorito de Sodio al 2.6% e Hidróxido de Sodio al 0.1n en la limpieza de Conductos Radiculares. Rev Odontol Latinoam. Vol.2(1):19-23. 2010

M De la Garza Ramos; L. A. Galán-Wong; Caffesse RG; B. Pereyra-Alférez; detection of porphyromonas gingivalis, tannerella forsytensis and streptococcus intermedius in dental plaque and saliva in young children by multiplex PCR. Industrial and Applied Microbiology. Vol. 3(4):525-528. 2010

A. De la Garza-Ramos; A. Alcázar-Pizaña; M. Garza-Enriquez; R. Caffesse, V. Aguirre- Arzola; L. J. Galán-Wong; B. Pereyra-Alférez.Streptococcus intermedius trigger quorum-sensing genes in porphyromonas gingivalis.Microorganisms in Industry dnd Environment. Vol. 3(4):518-521. 2010

Libros y Capítulos de Libros:

De la Garza Ramos M. A; Rodríguez Luis, O. E; Patricia G. P. Manual y cuaderno de trabajo de prácticas de microbiología oral. Colaboradoras: Escamilla García E.: Práctica 2. Coloración simple. Preparación de una extensión en el portaobjetos. Alcázar Pizaña A. G.: Práctica 13. Reacción en Cadena de la Polimerasa. 3a edición. Editorial El Manual Moderno, S.A. de C.V. Páginas: 151. ISBN: 978-607-448-431-1. 2014

De la Garza Ramos M.A; Escamilla García E. Financiamiento en la Investigación y Biotecnología en la Odontología (Aprovechamiento de residuos generados en la industria de alimentos. Uso de herramientas biotecnológicas para una nueva aplicación). En Compañías de Biotecnología Públicas y Privadas a Nivel Mundial. Su poder, éxito y futuro. Editor: Luis J. Galán Wong. 2ª Edición. Ediciones del Instituto de Biotecnología. ISBN-970-694-408-7. 2013

Capítulo: Estrategia para el desarrollo de procesos biotecnológicos. La UANL, pionera en investigación y desarrollo en ciencias de la salud. REVISTA DE DIVULGACIÒN: Ciencia Conocimiento Tecnología^MR. Revista mensual. Editor: Dr. Luis Eugenio Todd Pérez. Número 116, Pp: 48-49. FOMIX, Conacyt-N.L.

Unit Personnel

PhD Myriam A. de la Garza Ramos, Unit Chief

Dental Surgeon, Master’s in Science with specialty in Microbiology, PhD in Sciences with specialty in Biotechnology. Dental School Professor. Member of the National Research System (SNI level I), since 2010. Member of the International Association for Dental Research, since 2002. Accredited Evaluator (RCEA) CONACYT in Biotechnology and Agricultural Areas, since 2011.

Research Areas:

Oral cavity Anaerobic Microbiology.
Antimicrobial effect of Pharmaceuticals.
Genic expression of microorganisms.
Microorganism detection in the oral cavity.
Epidemiologic studies in indigenous communities.
New dental material usage and biocompatibility of materials.

PhD. Erandi Escamilla García.

Microbial Biochemist and Biotechnology.

PTC-A Researcher

Research of biological and natural alternatives for the prevention and treatment of oral diseases caused by microorganisms.
Study on the antimicrobial and bactericide properties of: 1) lactic acid bacteria and its metabolites, 2) natural extracts and organic residue of industrial processes.
Development and assistance to projects of microbial biochemistry, biotechnology, and microbial regulation processes in bioreactors areas.
Member of the Biosafety Committees (since 2011) and Research ( 2014) of the CIDICS.

Member of the Mexican Science Academy, since 2010.

PhD. Andrea G. Alcázar Pizaña. Proteomic and Biotechnology

Biochemical Engineer by the Technical Institute of Durango. Master’s in Sciences in Biochemical Engineering. PhD in Sciences with specialty in Biotechnology by the Biological Sciences School, UANL.

Research Areas:

Proteins produced by pathogens in the oral cavity and its relation to virulence.
Biochemical Mechanisms in the formation of Biofilms.

Projects

Study of the production and inhibition of proteases of Porphyromas gingivalis using plant extracts.
Gene expression involved in the production of Biofilm by oral cavity microorganisms.
Antimicrobial activity of Calcium hydroxide combined with Oxoral against Porphyromonas endodontalis and Enterococcus faecalis.
Proteases inhibition produced by Porphyromonas gingivalis using Jatropha dioica PAICyT, Key: CN347-1.

Postgraduate and Bachelor’s Degree Thesis

Proteases inhibition produced by Porphyromonas gingivalis using Jatropha dioica.
Growth and development of Streptococcus mutans in cultivation means containing various sweeteners.
Antimicrobial activity of Calcium hydroxide combined with Oxoral against Porphyromonas endodontalis and Enterococcus faecalis.
Gene expression of Streptococcus mutans involved in the formation of Biofilms in cultivation means supplemented with sweeteners.
Thesis Adviser: Master’s Degree.
Rheumatoid factor as a Biomarker in Parotid saliva on patients with Sjögren Syndrome and Severe Periodontal Disease.
IgA as a biomarker in Parotid saliva of patients with Sjögren Syndrome and its relation with periodontal disease, PhD.
Depression as a risk factor on chronic periodontitis on adults and its quality of life.
Protease inhibition produced by pathogen microorganisms in the oral cavity.
Gene expression involved in Biofilm production by oral cavity microorganisms.
Member of the International Association for Dental Research (2011-2012).

Dentist Salvador Pinales Armendáriz.

Dental Material

Biomechanical studies and temporomandibular joint simulator model development.